Postdoctoral Researcher - Complex Human Ex Vivo Models of Tissue Inflammation

Complex Human Ex Vivo Models of Tissue Inflammation (CHM)

About BioMed X

BioMed X is an independent research institute with sites in Heidelberg, Germany, New Haven, Connecticut, XSeed Labs in Ridgefield, Connecticut, and a worldwide network of partner locations.

Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds - academia and industry - and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.

About Team CHM

Arteries are crucial to maintaining health and are compromised in multiple diseases. Current in vitro and in vivo models to study this complex tissue are labor-intensive and insufficient to understand human disease initiation, development, and resolution. Our group, led by Dr. Alicia Cutler, is bridging this gap by generating a de novo 3D in vitro artery with sufficient complexity to recapitulate key characteristics of arterial structure and function to mimic vessel inflammation. We will deploy this organotypic human arterial model to investigate the generation, progression, and resolution of vasculitis with the long-term goal of advancing patient treatment and curing disease.

The Position

We are looking for a highly enthusiastic post-doctoral researcher to help drive the development of our artery model. We need a strong immunologist or cell biologist who can take initiative on inducing and characterizing vessel inflammation, isolating primary cells, and developing longitudinal assays. The ideal candidate would have a Ph.D. degree or equivalent in immunology or cell biology and a strong background in mammalian cell culture. Experience culturing human primary cells is particularly desirable.

Required skills

• Expertise in immunology.
• Extensive cell culture experience is essential.
• Ability to independently design, plan, execute, and interpret experiments.
• Excellent communication skills.

Additional skills as an asset to the position

• Experience with macrophage polarization and invasion.
• Experience maintaining primary human cell culture.
• Familiarity with 3D culture practices.
• Flow cytometry experience.
• Fluorescence microscopy experience.

What we offer

• The position is fully funded by AbbVie for a 2-to-4-year period and immediately available.
• NIH-Aligned salary with employee benefits plan.
• International, diverse, and positive work atmosphere with a flexible working environment.
• Access to a vast scientific network.

Candidates are requested to submit

• A one-pager cover letter explaining your interest in joining our team.
• An updated Curriculum Vitae outlining scientific interests, research achievements, record of publications, future personal goals, and extra-scientific passions.
• 2 references.
• A valid US work authorization is required for this position

Please submit your application by adding your updated CV, Cover Letter and references to the attention of Dr. Alicia Cutler by 03/15/2025, via our online application system: https://career.bio.mx/job/2025-NHV-J01

Applicants will be reviewed and interviewed on a rolling basis.

At BioMed X we embrace diversity as we consider it the source of innovation. We are committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, ideology, sex, sexual orientation, age, gender identity or gender expression, national origin, or disability.

Feel free to reach out if you have any questions: spal@bio.mx or cutler@bio.mx

To read about us, please visit: https://bio.mx/