Research Assistant Position - Complex Human Ex Vivo Models of Tissue Inflammation

About BioMed X

BioMed X is an independent research institute with sites in Heidelberg, Germany, New Haven, Connecticut, XSeed Labs in Ridgefield, Connecticut, and a world-wide network of partner locations. We operate at the interface between academia and industry, performing biomedical research and drug discovery & development in the fields of oncology, immunology, neuroscience, platform technologies, and artificial intelligence. All our research projects are sponsored by leading pharmaceutical companies and conducted by early-career scientists recruited from the best schools around the world. The combination of global crowdsourcing with local incubation of the best research talents and ideas allows us to solve the biggest challenges in biomedical research. We stand for free, creative, and curiosity-driven research combined with a solid validation of results, timelines, and deliverables. We serve a large purpose in advancing translational biomedicine by leveraging synergies and fostering cross-pollination across disciplines.

About Team CHM

Arteries are crucial to maintain health and are compromised in multiple diseases. Current in vitro and in vivo models to study this complex tissue are labor-intensive and insufficient to understand human disease initiation, development, and resolution. Our group, led by Dr. Alicia Cutler, is bridging this gap by generating a de novo 3D in vitro artery with sufficient complexity to recapitulate key characteristics of arterial structure and function to mimic disease. We will deploy this organotypic human arterial model to investigate the generation, progression, and resolution of vasculitis with the long-term goal of advancing patient treatment and curing disease.

The Position

For our site in New Haven, CT, USA, we are looking for highly enthusiastic researchers to support our efforts with their intellectual power and technical excellence. The ideal candidate would have a BS degree in immunology, cell/molecular biology, or bioengineering combined with strong experience in mammalian cell culture and aseptic technique.

Required skills

• Mastery of basic laboratory skills (pipetting, dilutions, concentration calculations, etc.)
• Expertise in mammalian cell culture
• Basic theoretical knowledge in statistics
• Excellent communication skills in English

Additional skills as an asset to the position

• Familiarity with fundamentals of inflammatory signaling
• Experience with immunocytochemistry or immunohistochemistry
• Experience with hydrogels or 3D culture systems

Candidates are requested to submit

• 1-page cover letter explaining the reasons of interest to join our team
• Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals, and extra-scientific passions
• 2 references

What we offer

The post is offered for a limited term until July 31st, 2025. * International, diverse, and positive work atmosphere, flexible working environment * A competitive salary * Access to training and lecture courses in house as well as in neighboring research institutions on the Life

Science Campus at Yale * Access to a vast network in science and industry * Employee benefits plan

The position is sponsored by AbbVie.

Please submit your application for the attention of Dr. Alicia Cutler before October 4th, 2024, via our online Career Space. Applicants will be reviewed and interviewed on a rolling basis and the position is available to fill starting October 7th, 2024.

At BioMed X we embrace diversity as we consider it the source of innovation. We are committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, ideology, sex, sexual orientation, age, gender identity or gender expression, national origin, or disability.