Postdoctoral Position (m/f/x) - Immunology & Neuroscience

About BioMed X

BioMed X is an independent research institute with sites in Heidelberg, Germany, New Haven, Connecticut, XSeed Labs in Ridgefield, Connecticut, and a worldwide network of partner locations. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds - academia and industry - and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.

About the Team

“Tracing Immune Cell Dysfunction in Autoimmunity and Neuroinflammation” is a diverse team of curious scientists with different backgrounds who work together to expand knowledge of human disease. Our goal is to understand the molecular mechanisms governing mitochondrial dysfunction and cellular senescence of immune cell populations in the context of autoimmunity and neuroinflammation. We use in vitro cell-based assays combined with proteomics, single-cell transcriptomics, and gene-editing techniques to identify and validate robust molecular signatures and potential drug candidates.

The Position

We are looking for an enthusiastic postdoctoral researcher to join our team and to broaden our think-tank with their intellectual power and technical excellence. You will work collaboratively with a group of scientists, and you will be responsible for the development of mechanistic studies to further our understanding of autoimmune and neuroinflammatory diseases. You will: * Develop and execute in vitro assays using primary human immune cells or cell lines * Analyze samples from patients * Independently design, execute and troubleshoot experiments, analyze and interpret data * Prepare data reports to the group leader and give presentations at internal and external meetings * Train and mentor student interns (Bachelor and Master students)

Required Skills

• Ph.D. degree in Cell Biology, Immunology, Biochemistry, Pharmacology, or a related field
• Ability to design and execute multi-color flow cytometry (preferred: spectral) staining of PBMCs (intracellular and surface staining)
• Excellent interpersonal and communication skills in English
• Demonstration of ownership and accountability
• Collaborative spirit, self-motivation and the ability to work in multiple sub-projects simultaneously
• Desire to learn, enthusiasm and passion for exploring new biology

Additional Preferred Skills

• Expertise in proteomics and/or sc-RNA-seq
• Demonstrated cell biology expertise including imaging techniques (confocal microscopy) and cell line engineering using CRISPR is desirable
• Candidates with good understanding of cell metabolism and mitochondria will be given preference.

What we offer

• International, diverse, and positive work atmosphere, flexible working environment
• A competitive salary
• Access to training and lecture courses in house as well as in neighboring research institutions on the Life Science Campus in Heidelberg
• Access to a vast network in science and industry.
• Job ticket, sponsored fitness contract, complimentary fresh fruit, soft drinks and chocolate, team recognition events, etc.

The position is available as of February 1st, 2024 and is offered for one year, with the possibility of extension for two additional years. The position is sponsored by Merck KGaA.

Candidates are requested to submit

• 1-page cover letter explaining the reasons of interest to join our team and an outline of the proposed contribution to the team
• Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals and extra-scientific passions
• 2 reference letters

Please submit your application to the attention of Dr. Gorjana Rackov before January 10th, 2024 via our online Career Space.