Job Offer #2023-BMX-J01 open until July 1, 2023
Postdoctoral Researcher (all genders) - Innate Immunity
23 days left to apply!
BioMed X is an independent research institute located on the campus of the University of Heidelberg in Germany. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with the local incubation of the world's brightest early-career research talents. Each highly diverse research team at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds - academia and industry - and enable breakthrough innovation by making biomedical research more efficient, agile, and fun.
About Translocation of Complex Macromolecules Across the Intestinal Epithelial Barrier (TMI)
The main objective of the research group TMI, headed by Dr. Kyungbo Kim, is to discover novel transport mechanisms in the human intestinal tract which could be utilized for oral-systemic delivery of diverse therapeutic modalities (e.g., peptides, oligonucleotides, and antibodies). Studies will involve isolating intestinal cells, generating intestinal organoids from human subjects, and creating an organotypic assay system of the intestine. The project's cores are to develop a ligand specific for a target cell and establish quantitative assessment methods to monitor macromolecular drug delivery across the intestinal epithelial barrier. Our final goal is to create a novel delivery platform that can be utilized to develop a new generation of oral immunotherapies to benefit patients.
For the open postdoctoral researcher position in Team TMI, we seek highly enthusiastic researchers to broaden our think tank with their intellectual power and technical excellence. The ideal candidate would have a PhD degree and strong background in immunology.
Hands-on experience in co-culture systems and technologies (e.g., Transwell® or OrganoPlate®)
Hands-on experience in the generation and culture of organoids
Theoretical/technical background in dendritic cell/macrophage biology
Strong experience with microscopy techniques (e.g., confocal microscopy & live-cell imaging)
Good documentation skills with close attention to detail
Excellent communication skills in English
Additional preferred skills
- Theoretical background in cell sorting and immune profiling (e.g., Flow cytometry)
- Hands-on experience in molecular biology techniques and genetic manipulation of cells (e.g., PCR, RNA isolation, western blotting, cloning, and gene overexpression/knockdown or gene knock-in/knock-out)
- Experienced in working in interdisciplinary teams
What we offer
- International, diverse, and positive work atmosphere, flexible working environment
- A competitive salary
- Access to training and lecture courses in-house as well as in neighboring research institutions on the Life Science Campus in Heidelberg
- Access to a vast network in science and industry
- Job ticket, sponsored fitness contract, complimentary fresh fruit, soft drinks and chocolate, team recognition events, etc.
The position is available as of 01 August 2023 for a fixed term until 31 July 2025. The position is sponsored by Janssen.
Candidates are requested to submit
- 1-page cover letter explaining the reasons for interest in joining our team
- Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals, and extra-scientific passions
- Two references
Please submit your application to the attention of Dr. Kyungbo Kim before 1 July 2023 via our online career space.