Job Offer #2021-J11 closed since October 15, 2021
PhD Student Position (all genders) Protective Tissue Factors in Autoimmune Diseases
About BioMed X
BioMed X is an independent research institute located on the campus of the University of Heidelberg in Germany. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds - academia and industry - and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.
About Team PTA
The main objective of the group, headed by Mojca Frank Bertoncelj MD PhD, is to understand the molecular mechanisms that promote pro-resolution responses in immune and stromal cells to restore homeostasis. In particular, the team will use the human synovium as a model system to characterize the pro-resolving phenotypes of macrophages in rheumatoid arthritis. The core of the project will be the development of a first in kind synovium-in-a-dish assay for systematic monitoring of macrophage functions utilizing diverse methodologies including single-cell omics, gene-editing, bio-scaffold manufacturing, and stem to adult joint cell differentiation. Our final goal is to identify new therapeutic targets, which promote pro-resolution in inflammation and autoimmune diseases, and thereby proposing novel concepts to improve patient outcomes.
For the open PhD student position in Team PTA, we are looking for highly enthusiastic researchers to broaden our think-tank with their intellectual power and technical excellence. The ideal candidate would have a MSc degree in computational biology/data science combined with basic knowledge of cell/tissue biology or experience in basic molecular/cell biology methods.
- Expertise in bioinformatic analysis and integration of omics data
- Expertise in bioinformatic analysis of single cell RNA-sequencing or spatial transcriptomics data would be a strong advantage
- Basic theoretical knowledge in cell/tissue biology
- Independent thinking
- Experienced to work in interdisciplinary teams
- Excellent communication skills in English
Additional skills as an asset to the position
- Basic experience in cell culture, experimenting with biological specimen (e.g. tissue, blood) or
- Basic experience in standard molecular biology methods (qPCR, Western blotting, ELISA) or
- Motivation to acquire basic experience in cell/molecular biology methodology and experimenting with human biological specimen
Candidates are requested to submit
- 1-page cover letter explaining the reasons of interest to join our team
- Curriculum Vitae outlining scientific interests, research achievements, a record of publications, future personal goals and extra-scientific passions
- 2 reference letters
What we offer
- International, diverse, and positive work atmosphere, flexible working environment
- A competitive salary
- Access to training and lecture courses in house as well as in neighboring research institutions on the Life Science Campus in Heidelberg
- Access to a vast scientific network.
- Job ticket, sponsored fitness contract, complimentary fresh fruit, soft drinks and chocolate, team recognition events, etc.
The post is offered for a limited term until July 31st, 2025. The position is available as of November 1st, 2021 and is sponsored by Janssen. Please submit your application to the attention of Dr. Mojca Frank-Bertoncelj before October 15th, 2021 via the application system on this website. Applicants will be interviewed upon incoming documents, hence please get in touch as soon as you decide to apply.